Visualization of fermentation process! Understand AI+visualization, virtual reality+immersive experience, multimodal and multi-scale fusion
The visualization technology of fermentation allows people to intuitively experience its mysteries.
Welcome everyone to the Bailun Songjiang Synthetic Biology Laboratory to experience the mysteries of biological reactions on site! Parallel bioreactors, synthetic biology laboratories, digital, intelligent, and precise biological reactions!
During the laboratory trial phase, visualization helps researchers quickly adjust fermentation parameters.
Taking the production of industrial enzyme preparations as an example, with the help of real-time monitoring under a microscope, it was found that when the fermentation temperature was fine tuned to 30 ℃ and the dissolved oxygen was controlled at 5mg/L, the efficiency of Bacillus subtilis synthase was significantly improved, and the enzyme activity increased by 20% per unit time, locking in key process conditions for subsequent scale-up production.
Various sensors and imaging devices installed on large fermentation tanks transmit massive amounts of data in real-time.
Once there is abnormal fluctuation in the data, it is like a health warning, informing operators in advance of possible bacterial contamination, substrate depletion, and other potential hazards.
In the antibiotic fermentation workshop of a large pharmaceutical company, it was detected through spectral analysis that impurity peaks appeared earlier and their intensity increased in the fermentation broth.
Immediate investigation revealed that it was caused by slight contamination of the raw materials, and timely measures were taken to ensure that the quality of each batch of drugs met the standards.
The research team used visualization methods to track the metabolic pathways of gene edited microorganisms throughout the process. When modifying Escherichia coli to produce biofuels, they observed in real time the dynamic process of the newly introduced genes promoting intracellular lipid droplet accumulation, and quickly iterated the strain modification plan.
The research and development cycle, which originally required several months, has now been shortened by nearly one-third, helping biofuels to move towards large-scale applications as soon as possible.
