Top 10 Revolutionary Challenges! Why are there so many difficulties and endless fantasies in synthetic biology?
1. Automation and Industrialization: Synthetic biology is moving towards automation to achieve standardization of biological components and rapid assembly of DNA. In the future, it is necessary to continuously build an integrated system that can efficiently design, construct, test, and learn, thereby accelerating the development of synthetic biology solutions.
2. Empowering DNA design with deep learning: Deep learning models are being trained to understand and generate DNA sequences. These models are expected to simplify the design process of genetic programs and directly write optimized DNA sequences through advanced commands.
3. Whole cell simulation: With the explosive growth of biological data, whole cell simulation will become possible. Whole cell simulation will help scientists predict the impact of gene editing on cells before actual construction, thereby improving the accuracy of design.
4. Biosensors: The development of biosensors will enable us to detect a wider range of molecules and environmental conditions. In the future, there will be a need for more, smarter, and more sensitive biosensors that can monitor health conditions or environmental changes in real time.
5. Real time precise control of evolution: Scientists are learning how to control the evolution process of organisms through technologies such as CRISPR. In the future, it is necessary to design biological systems that can self optimize to adapt to constantly changing environments.
6. Cell community and multicellular nature: One of the goals of synthetic biology is to create synthetic communities that can simulate natural multicellular biological behavior. This will involve communication, cooperation, and differentiation between cells to achieve more complex functions.
7. Customization and dynamic synthesis of genomes: Research on synthetic genomes is moving towards customization, and in the future, genomes may be designed for specific applications. In addition, the concept of dynamic genomes is also being explored, which have characteristics that change according to environmental signals.
8. Artificial cell reconstruction: The research on artificial cells aims to reconstruct the basic functions of cells from their basic biochemical components. These cells will help us understand the boundaries of life and may provide new platforms for biotechnology applications in the future.
9. Production of DNA encoded properties of materials: Research on engineered biomaterials (ELMs) is on the rise, which are produced by genetically programmed cells and exhibit specific chemical and physical properties, providing new avenues for the development of sustainable materials.
10. Sustainable Biodesign: Synthetic biology has enormous potential in addressing global sustainability issues. Engineering biology can help us develop renewable energy, reduce waste, enhance ecosystem diversity, and improve the sustainability of food production.
